WINE is a compatibility layer for Linux that lets you run Windows applications and games without a full Windows OS. It translates Windows system calls into Linux ones, enabling native-like performance and integration.

Proton is a Steam-developed compatibility layer for Linux that runs Windows games seamlessly. Built on WINE, it adds gaming-focused enhancements, like DirectX translation and performance optimizations, for smooth gameplay.

GE-Proton (previously Proton-GE) is a community-maintained variant of Proton with additional patches. It provides alternative fixes and enhancements for running Windows games on Linux, complementing the official Proton builds.

Proton-Sarek, based on Proton, is designed for older or low-end GPUs. It uses DXVK 1.10.x and patched WineD3D to improve compatibility with Vulkan 1.1+ hardware, ensuring more games run smoothly without modern GPU features.

Proton-GE-Custom is a variant of GE-Proton that offers user-friendly builds and installation. It provides additional tweaks and patches to improve compatibility and performance for running Windows games on Linux systems.

Xemu is an open-source Xbox emulator for Linux that runs original Xbox games. It emulates the console’s hardware and software environment, enabling controller support, graphics options, and save features for PC gameplay.

RPCS3 is a PlayStation 3 emulator for Linux, allowing many PS3 games to run on PC. It provides configurable graphics, audio, and controls, translating PS3 operations to desktop systems for playable performance.

PCSX2 is a PlayStation 2 emulator for Linux that lets you play PS2 games on a PC. It translates PS2 instructions into computer commands, supporting enhanced graphics, save states, and controller input for a playable experience.